Muscarine (chloride)

Muscarine ((+) -Muscarine) chloride is an agonist of prototype mAChR. Muscarine chloride is a toxin that can stimulate the parasympathetic nervous system[1][2].

Product Specifications

CAS Number

[2303-35-7]

Product Name Alternative

(+) -Muscarine (chloride)

UNSPSC

12352005

Hazard Statement

H300+H310+H330

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/muscarine-chloride.html

Purity

99.0

Solubility

H2O : 50 mg/mL (ultrasonic; warming)

Smiles

C[C@H]1[C@@H](C[C@H](O1)C[N+](C)(C)C)O.[Cl-]

Molecular Formula

C9H20ClNO2

Molecular Weight

209.71

Precautions

H300+H310+H330

References & Citations

[1]Beatrice Mihaela Radu, et al. All muscarinic acetylcholine receptors (M 1-M 5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017 Jul 11;7 (1) :5083.|[2]Z Z Pan, et al. Muscarine hyperpolarizes a subpopulation of neurons by activating an M2 muscarinic receptor in rat nucleus raphe magnus in vitro. J Neurosci. 1994 Mar;14 (3 Pt 1) :1332-8.