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L-659,989

L-659,989 is an orally active, extremely potent, selective and competitive platelet activating factor (PAF) receptor antagonist[1].

Product Specifications

CAS Number

113787-28-3

UNSPSC

12352005

Target

Platelet-activating Factor Receptor (PAFR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-659-989.html

Solubility

10 mM in DMSO

Smiles

COC1=C(C(OC)=CC([C@@H]2CC[C@H](O2)C3=CC(S(=O)(C)=O)=C(C(OC)=C3)OCCC)=C1)OC

Molecular Formula

C24H32O8S

Molecular Weight

480.57

References & Citations

[1]Hwang SB, et al. Biochemical and pharmacological characterization of L-659,989: an extremely potent, selective and competitive receptor antagonist of platelet-activating factor. J Pharmacol Exp Ther. 1988 Aug;246 (2) :534-41.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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