L-659,989
L-659,989 is an orally active, extremely potent, selective and competitive platelet activating factor (PAF) receptor antagonist[1].
Product Specifications
CAS Number
113787-28-3
UNSPSC
12352005
Target
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-659-989.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C(OC)=CC([C@@H]2CC[C@H](O2)C3=CC(S(=O)(C)=O)=C(C(OC)=C3)OCCC)=C1)OC
Molecular Formula
C24H32O8S
Molecular Weight
480.57
References & Citations
[1]Hwang SB, et al. Biochemical and pharmacological characterization of L-659,989: an extremely potent, selective and competitive receptor antagonist of platelet-activating factor. J Pharmacol Exp Ther. 1988 Aug;246 (2) :534-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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