Lasiocarpine
Product Specifications
UNSPSC Description
Lasiocarpine, a hepatotoxic pyrrolizidine alkaloid (PA), causes fatal liver veno-occlusive disease in vivo. Lasiocarpine is toxic only after its metabolic conversion to the toxic intermediate, including dehydrolasiocarpine and N-oxide[1].
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lasiocarpine.html
Solubility
10 mM in DMSO
Smiles
CO[C@H](C)[C@](C(C)(O)C)(O)C(OCC1=CCN2[C@@]1([H])[C@@H](OC(/C(C)=C\C)=O)CC2)=O
Molecular Weight
411.49
References & Citations
[1]Muluneh M Fashe, et al. Species-Specific Differences in the in Vitro Metabolism of Lasiocarpine. Chem Res Toxicol. 2015 Oct 19;28(10):2034-44.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121390/Lasiocarpine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121390/
Clinical Information
No Development Reported
CAS Number
303-34-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
