Indecainide
Indecainide (Ricainide) is an orally active antiarrhythmic agent. Indecainide can be used in the research of ventricular dysfunction. Indecainide has Na+-channel-blocking activity[1][2].
Product Specifications
CAS Number
74517-78-5
Product Name Alternative
Ricainide; LY 135837 (free base)
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/indecainide.html
Solubility
10 mM in DMSO
Smiles
O=C(N)C1(C2=C(C=CC=C2)C3=C1C=CC=C3)CCCNC(C)C
Molecular Formula
C20H24N2O
Molecular Weight
308.42
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14 (3) :454-61. |[2]Lindstrom T D, et al. Metabolism of the antiarrhythmic agent, indecainide, in rats, dogs, and monkeys. Drug metabolism and disposition, 1984, 12 (6) : 691-697.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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