Indecainide

Indecainide (Ricainide) is an orally active antiarrhythmic agent. Indecainide can be used in the research of ventricular dysfunction. Indecainide has Na+-channel-blocking activity[1][2].

Product Specifications

CAS Number

[74517-78-5]

Product Name Alternative

Ricainide; LY 135837 (free base)

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/indecainide.html

Solubility

10 mM in DMSO

Smiles

O=C(N)C1(C2=C(C=CC=C2)C3=C1C=CC=C3)CCCNC(C)C

Molecular Formula

C20H24N2O

Molecular Weight

308.42

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14 (3) :454-61. |[2]Lindstrom T D, et al. Metabolism of the antiarrhythmic agent, indecainide, in rats, dogs, and monkeys. Drug metabolism and disposition, 1984, 12 (6) : 691-697.