Kendomycin
Kendomycin ((−) -TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 μg/mL) . Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent[1][2].
Product Specifications
CAS Number
183202-73-5
Product Name Alternative
(-) -TAN2162
UNSPSC
12352005
Target
Antibiotic; Bacterial; CGRP Receptor; Endothelin Receptor
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/kendomycin.html
Purity
98.00
Solubility
DMSO : 1 mg/mL (ultrasonic; warming)
Smiles
OC(C1=O)=C([C@]([C@@H]([C@H]2O)C)([H])O[C@@](CC[C@@H]3C)([H])[C@@H]2C)C(C(O4)=C1C)=C[C@@]4([C@H](C[C@@H](C/C(C)=C/3)C)C)O
Molecular Formula
C29H42O6
Molecular Weight
486.64
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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