Aureothin
Aureothin, is a natural polyketide, is a HIV inhibitor with an IC50 of 5.3 nM. Aureothin is a microbial biolarvicide[1][2].
Product Specifications
CAS Number
[2825-00-5]
UNSPSC
12352005
Hazard Statement
H300+H310, H319, H332
Target
HIV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/aureothin.html
Solubility
10 mM in DMSO
Smiles
CC1=C([C@H]2C/C(CO2)=C/C(C)=C/C3=CC=C(C=C3)[N+]([O-])=O)OC(OC)=C(C1=O)C
Molecular Formula
C22H23NO6
Molecular Weight
397.42
Precautions
H300+H310, H319, H332
References & Citations
[1]Seong Jong Kim, et al. Streptomyces distallicus, a Potential Microbial Biolarvicide. J Agric Food Chem. 2022 Sep 14;70 (36) :11274-11280.|[2]Alexander Herrmann, et al. Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin. Sci Rep. 2020 Jan 28;10 (1) :1326.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121291/Aureothin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121291/
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HIV
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