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Aureothin

Aureothin, is a natural polyketide, is a HIV inhibitor with an IC50 of 5.3 nM. Aureothin is a microbial biolarvicide[1][2].

Product Specifications

CAS Number

[2825-00-5]

UNSPSC

12352005

Hazard Statement

H300+H310, H319, H332

Target

HIV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/aureothin.html

Solubility

10 mM in DMSO

Smiles

CC1=C([C@H]2C/C(CO2)=C/C(C)=C/C3=CC=C(C=C3)[N+]([O-])=O)OC(OC)=C(C1=O)C

Molecular Formula

C22H23NO6

Molecular Weight

397.42

Precautions

H300+H310, H319, H332

References & Citations

[1]Seong Jong Kim, et al. Streptomyces distallicus, a Potential Microbial Biolarvicide. J Agric Food Chem. 2022 Sep 14;70 (36) :11274-11280.|[2]Alexander Herrmann, et al. Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin. Sci Rep. 2020 Jan 28;10 (1) :1326.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

HIV

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