Benzotript
Benzotript (Benzotriptum) is a cholecystokinin-receptor (CCK) and gastrin receptor antagonist. Benzotript shows antiproliferative effects in human colon carcinoma cell lines[1].
Product Specifications
CAS Number
39544-74-6
Product Name Alternative
Benzotriptum
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cholecystokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/benzotript.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC(C1=CC=C(C=C1)Cl)=O)CC2=CNC3=C2C=CC=C3)O
Molecular Formula
C18H15ClN2O3
Molecular Weight
342.78
Precautions
H302, H315, H319, H335
References & Citations
[1]N M Hoosein, et al. Antiproliferative effects of gastrin receptor antagonists and antibodies to gastrin on human colon carcinoma cell lines. Cancer Res. 1988 Dec 15;48 (24 Pt 1) :7179-83.|[2]C Niederau, et al. Caerulein-induced acute necrotizing pancreatitis in mice: protective effects of proglumide, benzotript, and secretin. Gastroenterology. 1985 May;88 (5 Pt 1) :1192-204.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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