Amiprilose

Amiprilose (SM1213; Therafectin) is a potent inhibitor against Hepatocellular carcinoma (HCC) . Amiprilose induces lymphokine-induced macrophage activation directly to kill Listeria monocytogenes[1][2].

Product Specifications

CAS Number

[56824-20-5]

Product Name Alternative

SM1213; Therafectin

UNSPSC

12352005

Hazard Statement

H301-H311-H315-H319-H331-H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/amiprilose.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]([C@H]1O[C@H]2[C@H](OC(C)(C)O2)[C@H]1OCCCN(C)C)CO

Molecular Formula

C14H27NO6

Molecular Weight

305.37

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501

References & Citations

[1]Wang XK, et al. Clinical significance of long non-coding RNA DUXAP8 and its protein coding genes in hepatocellular carcinoma. J Cancer. 2020 Aug 25;11 (20) :6140-6156. |[2]Hadden JW. Effects of isoprinosine, levamisole, muramyl dipeptide, and SM1213 on lymphocyte and macrophage function in vitro. Cancer Treat Rep. 1978 Nov;62 (11) :1981-5.