Butibufen

Butibufen is an orally active non-steroidal compound. Butibufen shows analgesic and antipyretic properties. Butibufen can be used for the research of inflammation[1][2].

Product Specifications

CAS Number

[55837-18-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Carbamoyl Phosphate Synthetase (CPS) ; Urea Transporter

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/butibufen.html

Solubility

10 mM in DMSO

Smiles

CCC(C(O)=O)C1=CC=C(C=C1)CC(C)C

Molecular Formula

C14H20O2

Molecular Weight

220.31

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Aparicio L. Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent. Arch Int Pharmacodyn Ther. 1977 May;227 (1) :130-41. |[2]Castell JV, et al. A study of the relative hepatotoxicity in vitro of the non-steroidal anti-inflammatory drugs ibuprofen, flurbiprofen and butibufen. Xenobiotica. 1988 Jun;18 (6) :737-45. |[3]Alamo C, et al. Influence of butibufen on enzyme activity and lysosomal stabilization ex vivo: a comparative study with hydrocortisone and acetylsalicylic acid. Methods Find Exp Clin Pharmacol.