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Fluindione

Fluindione is a inhibitor of 5-lipoxygenase with the IC50 of 15 μM. Fluindione has antiinflammatory activity[1].

Product Specifications

CAS Number

[957-56-2]

UNSPSC

12352005

Hazard Statement

H301, H315, H319, H335

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/fluindione.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C(C2=C1C=CC=C2)=O)C3=CC=C(C=C3)F

Molecular Formula

C15H9FO2

Molecular Weight

240.23

Precautions

H301, H315, H319, H335

References & Citations

[1]Brooks, et al. Structural analysis of 2-aryl-1,3-dione compounds as inhibitors of 5-lipoxygenase. Bioorganic & Medicinal Chemistry Letters, 2 (10), 1309–1314.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound1

Clinical Information

Phase 4

Curated Selection

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