Diapocynin

Diapocynin (Dehydrodiacetovanillone), a dimeric derivative of Apocynin, is an orally active NADPH oxidase inhibitor. Diapocynin has anti-inflammatory, neuroprotection and antioxidant activities[1].

Product Specifications

CAS Number

[29799-22-2]

Product Name Alternative

Dehydrodiacetovanillone

UNSPSC

12352005

Hazard Statement

H410

Target

NADPH Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/diapocynin.html

Concentration

10mM

Purity

99.0

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

COC1=CC(C(C)=O)=CC(C2=C(O)C(OC)=CC(C(C)=O)=C2)=C1O

Molecular Formula

C18H18O6

Molecular Weight

330.33

Precautions

H410

References & Citations

[1]Marson Putra, et al. Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate-induced long-term neurotoxicity in the rat model. Ann N Y Acad Sci. 2020 Nov;1479 (1) :75-93.