Ceefourin 2
Product Specifications
UNSPSC Description
Ceefourin 2 is a potent and highly selective inhibitor of MRP4. Ceefourin 2 inhibits the transport of MRP4 substrates but is not selective for other ABC transporters. Ceefourin 2 shows lower cytotoxicity and higher microsomal and acid stability[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/ceefourin-2.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=NN2C(C(F)(F)F)=CC(C3=CC=C(C=C3)C)=NC2=C1Cl
Molecular Weight
355.70
References & Citations
[1]Cheung L, et al. High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4). Biochem Pharmacol. 2014 Sep 1;91(1):97-108.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121088/Ceefourin-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121088/
Clinical Information
No Development Reported
CAS Number
348148-51-6
Curated Selection
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