ASS234
ASS234 is a potent monoamino oxidase (MAO) inhibitor with IC50s of 5.2 nM and 43 nM for MAO-A and MAO-B, respectively. ASS234 also inhibits AChE and BuChE with IC50s of 350 nM and 460 nM, respectively[1].
Product Specifications
CAS Number
1334106-34-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cholinesterase (ChE) ; Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ass234.html
Purity
99.6
Solubility
10 mM in DMSO
Smiles
C#CCN(C)CC1=CC2=C(C=CC(OCCCC3CCN(CC3)CC4=CC=CC=C4)=C2)N1C
Molecular Formula
C29H37N3O
Molecular Weight
443.62
Precautions
H302, H315, H319, H335
References & Citations
[1]Anna Stasiak, et al. Effects of novel monoamine oxidases and cholinesterases targeting compounds on brain neurotransmitters and behavior in rat model of vascular dementia. Curr Pharm Des. 2014;20 (2) :161-71.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE; MAO-A; MAO-B
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