Chamazulene
Chamazulene, a natural compound, is an antioxidant-type inhibitor of leukotriene B4 formation[1].
Product Specifications
CAS Number
[529-05-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Leukotriene Receptor; MMP; NF-κB
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/chamazulene.html
Purity
98.96
Solubility
10 mM in DMSO
Smiles
CC1=C2C(C=C1)=C(C=CC(CC)=C2)C
Molecular Formula
C14H16
Molecular Weight
184.28
Precautions
H302, H315, H319, H335
References & Citations
[1]H Safayhi, et al. Chamazulene: an antioxidant-type inhibitor of leukotriene B4 formation. Planta Med. 1994 Oct;60 (5) :410-3.|[2]Andrea Capuzzo, et al. Antioxidant and radical scavenging activities of chamazulene. Nat Prod Res. 2014;28 (24) :2321-3.|[3]Ding Ma, et al. Chamazulene reverses osteoarthritic inflammation through regulation of matrix metalloproteinases (MMPs) and NF-kβpathway in in-vitro and in-vivo models. Biosci Biotechnol Biochem. 2020 Feb;84 (2) :402-410.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
MMP-3; MMP-9
Available Sizes
Curated Selection
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