CB1 inverse agonist 2

CB1 inverse agonist 2 is an orally active inverse agonist of Cannabinoid Receptor CB1. CB1 inverse agonist 2 effectively inhibits CP55940-induced hypothermia and anorexia in mice model[1].

Product Specifications

CAS Number

[1019839-52-1]

UNSPSC

12352005

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cb1-inverse-agonist-2.html

Purity

99.15

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C2SC3=CC=CC=C3C(C4=CC=C(F)C(Cl)=C4)=NC2=C1)NCCCC

Molecular Formula

C24H20ClFN2OS

Molecular Weight

438.94

References & Citations

[1]Synthesis and Evaluation of Dibenzothiazepines: A Novel Class of Selective Cannabinoid-1 Receptor Inverse Agonists J. Med. Chem., 2009, 52 (7), pp 1975-1982|[2]Pettersson H, et al. Synthesis and evaluation of dibenzothiazepines: a novel class of selective cannabinoid-1 receptor inverse agonists. J Med Chem. 2009 Apr 9;52 (7) :1975-82.