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BAY-7598

BAY-7598, a chemical probe, is a potent, orally bioavailable, and selective MMP12 inhibitor with IC50s of 0.085, 0.67 and 1.1 nM for human MMP12, murine MMP12, and rat MMP12, respectively[1].

Product Specifications

CAS Number

[1816257-74-5]

UNSPSC

12352005

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bay-7598.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1[C@H](CN2N=NC3=CC=CC=C3C2=O)CC[C@@H]1C(C4=CC=C(OCCC5CCOCC5)C=C4)=O)O

Molecular Formula

C28H31N3O6

Molecular Weight

505.56

References & Citations

[1]Chemical Probe BAY-7598 MMP12 Inhibitor.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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