BAY-7598
BAY-7598, a chemical probe, is a potent, orally bioavailable, and selective MMP12 inhibitor with IC50s of 0.085, 0.67 and 1.1 nM for human MMP12, murine MMP12, and rat MMP12, respectively[1].
Product Specifications
CAS Number
[1816257-74-5]
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bay-7598.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1[C@H](CN2N=NC3=CC=CC=C3C2=O)CC[C@@H]1C(C4=CC=C(OCCC5CCOCC5)C=C4)=O)O
Molecular Formula
C28H31N3O6
Molecular Weight
505.56
References & Citations
[1]Chemical Probe BAY-7598 MMP12 Inhibitor.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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