DBCO-C3-Acid
DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker[1].
Product Specifications
CAS Number
[1207355-31-4]
UNSPSC
12352203
Hazard Statement
H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-c3-acid.html
Purity
99.68
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCCC(O)=O)N1CC2=CC=CC=C2C#CC3=CC=CC=C31
Molecular Formula
C20H17NO3
Molecular Weight
319.36
Precautions
H315, H319, H335
References & Citations
[1]van Geel R, et al. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody-Drug Conjugates. Bioconjug Chem. 2015;26 (11) :2233-2242.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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