Yhhu-3792 (hydrochloride)
Yhhu-3792 hydrochloride is a Notch activator. Yhhu-3792 hydrochloride enhances the self-renewal capability of neural stem cells (NSCs) . Yhhu-3792 hydrochloride promotes the expression of Hes3 and Hes5. Yhhu-3792 hydrochloride increases the spatial and episodic memory abilities of mice. Thhu-3792 can be used for the treatment of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury[1] [2].
Product Specifications
CAS Number
[2624336-93-0]
UNSPSC
12352005
Target
Notch
Type
Reference compound
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/yhhu-3792-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
[H]Cl.NC1=C2C(OC3=CC=CC(OC)=C3)=CC=CC2=NC(NC4=CC=C(C(C)C)C=C4)=N1
Molecular Formula
C24H25ClN4O2
Molecular Weight
436.93
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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