Boc-NH-PEG1-CH2CH2COOH
Boc-NH-PEG1-CH2CH2COOH is a cleavable (1 unit PEG) ADC linker and also a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of antibody-drug conjugates (ADCs) or PROTACs[1][2].
Product Specifications
CAS Number
1260092-44-1
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-nh-peg1-ch2ch2cooh.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
CC(C)(OC(NCCOCCC(O)=O)=O)C
Molecular Formula
C10H19NO5
Molecular Weight
233.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Darren H. Wakefield, et al. Poly (vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.|[2]Alex Cortez, et al.Antibody conjugates comprising toll-like receptor agonist and combination therapies. WO2018198091A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
Frequently Asked Questions
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