Pimprinine

Pimprinine is a potent monoamine oxidase inhibitor, could be isolated from fermented broths. Pimprinine has antioxidative activity and anticonvulsant activity. Pimprinine inhibits tremorine-induced tremors and analgesia in mice[1][2][3].

Product Specifications

CAS Number

[13640-26-1]

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pimprinine.html

Purity

90.0

Solubility

10 mM in DMSO

Smiles

CC1=NC=C(C2=CNC3=C2C=CC=C3)O1

Molecular Formula

C12H10N2O

Molecular Weight

198.22

References & Citations

[1]Takeuchi T, et, al. Monoamine oxidase inhibitors isolated from fermented broths. J Antibiot (Tokyo) . 1973 Mar;26 (3) :162-7.|[2]Miao YP, et, al. Synthesis and antioxidative activity of 2-substituted phenyl-5- (3'-indolyl) -oxazole derivatives. Yao Xue Xue Bao. 2004 Jan;39 (1) :37-40.|[3]Naik SR, et, al. Pimprinine, an extracellular alkaloid produced by Streptomyces CDRIL-312: fermentation, isolation and pharmacological activity. J Biotechnol. 2001 Jun 1;88 (1) :1-10.