S-14671
S-14671 is a high-affinity 5-HT1A agonist (pKi=9.3) . S-14671 can be used for research on neurological diseases, such as anti-anxiety, anti-depression, etc[1].
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-14671.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCN1CCN(CC1)C2=C3C=C(C=CC3=CC=C2)OC)C4=CC=CS4
Molecular Formula
C22H25N3O2S
Molecular Weight
395.52
References & Citations
[1]Millan MJ, et al. S 14671: a novel naphthylpiperazine 5-HT1A agonist of high efficacy and exceptional in vivo potency. Eur J Pharmacol. 1991 Oct 15;203 (2) :319-22.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120686/S-14671-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120686/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; mLAG-3
CAS Number
[135722-27-9]
Curated Selection
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