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S-14671

S-14671 is a high-affinity 5-HT1A agonist (pKi=9.3) . S-14671 can be used for research on neurological diseases, such as anti-anxiety, anti-depression, etc[1].

Product Specifications

CAS Number

135722-27-9

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-14671.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCN1CCN(CC1)C2=C3C=C(C=CC3=CC=C2)OC)C4=CC=CS4

Molecular Formula

C22H25N3O2S

Molecular Weight

395.52

References & Citations

[1]Millan MJ, et al. S 14671: a novel naphthylpiperazine 5-HT1A agonist of high efficacy and exceptional in vivo potency. Eur J Pharmacol. 1991 Oct 15;203 (2) :319-22.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT1 Receptor; mLAG-3

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