EP6
EP6 is a potent 5-Lipoxygenase (5-LO) inhibitor. EP6 inhibits the cell viability of tumor cells without mutagenic activity. EP6 can be used in research of cancer[1].
Product Specifications
CAS Number
1353567-32-4
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ep6.html
Solubility
10 mM in DMSO
Smiles
CC1=CN2C(C=C1)=NC(C3=CC=C(C=C3)N4CCOCC4)=C2NC5CCCCC5
Molecular Formula
C24H30N4O
Molecular Weight
390.52
References & Citations
[1]Wisniewska JM, et, al. Molecular characterization of EP6--a novel imidazo[1,2-a]pyridine based direct 5-lipoxygenase inhibitor. Biochem Pharmacol. 2012 Jan 15;83 (2) :228-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-LOX
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