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EP6

EP6 is a potent 5-Lipoxygenase (5-LO) inhibitor. EP6 inhibits the cell viability of tumor cells without mutagenic activity. EP6 can be used in research of cancer[1].

Product Specifications

CAS Number

[1353567-32-4]

UNSPSC

12352005

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ep6.html

Solubility

10 mM in DMSO

Smiles

CC1=CN2C(C=C1)=NC(C3=CC=C(C=C3)N4CCOCC4)=C2NC5CCCCC5

Molecular Formula

C24H30N4O

Molecular Weight

390.52

References & Citations

[1]Wisniewska JM, et, al. Molecular characterization of EP6--a novel imidazo[1,2-a]pyridine based direct 5-lipoxygenase inhibitor. Biochem Pharmacol. 2012 Jan 15;83 (2) :228-40.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-LOX

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