BMS-200
BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 80 nM. BMS-200 can induce dimerization of PD-L1[1].
Product Specifications
CAS Number
1675203-82-3
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bms-200.html
Purity
98.02
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C[C@H](O)CNCC1=CC(F)=C(OCC2=CC=CC(C3=CC=C(OCCO4)C4=C3)=C2C)C=C1F
Molecular Formula
C27H27F2NO6
Molecular Weight
499.50
References & Citations
[1]Katarzyna Guzik, et al. Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1. J Med Chem. 2017 Jul 13;60 (13) :5857-5867.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
R0270r 1 Each
Rat Lat / Linker for activation of T-cells family member 1 Recombinant Protein
Sign In for Pricing
View Details 
GTR15323794 1 Vial
Lentiviral human PNMA6A shRNA (UAS) - Lentiviral human PNMA6A shRNA (UAS) plasmid
Sign In for Pricing
View Details