XZH-5
XZH-5 inhibits the phosphorylation of STAT3 and results in the induction of apoptosis and reduction of colony forming ability[1].
Product Specifications
CAS Number
[1360562-98-6]
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/xzh-5.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)[C@H](CC1=CN(C)C=N1)NC([C@H](C(C)C)NC(NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=O)=O
Molecular Formula
C22H25F6N5O4
Molecular Weight
537.46
References & Citations
[1]Li Chenglong, et al. Compound XZH-5 inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human hepatocellular carcinoma cells. World Intellectual Property Organization, WO2012078982 A2 2012-06-14
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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