FR221647
FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. FR221647 is not cytotoxic at a concentration of 100 μM[1].
Product Specifications
CAS Number
256461-28-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Adenosine Deaminase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fr221647.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(C(CO)CCC2=CC=CC=C2)C=N1)N
Molecular Formula
C14H17N3O2
Molecular Weight
259.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Terasaka T, et al. Structure-based de novo design of non-nucleoside adenosine deaminase inhibitors. Bioorg Med Chem Lett. 2003 Mar 24;13 (6) :1115-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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