GR 128107

GR 128107 is a competitive melatonin receptor antagonist (pKi: 9.6) [1].

Product Specifications

CAS Number

[190328-44-0]

UNSPSC

12352005

Target

Melatonin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gr-128107.html

Solubility

10 mM in DMSO

Smiles

CC(N1CC(CCC1)C2=CNC3=C2C=C(C=C3)OC)=O

Molecular Formula

C16H20N2O2

Molecular Weight

272.34

References & Citations

[1]Dubocovich ML, et al. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355 (3) :365-75.