FR181157
FR181157, an orally active PGI2 agonist activity with especially good pharmacokinetic properties[1].
Product Specifications
CAS Number
[171046-15-4]
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fr181157.html
Solubility
10 mM in DMSO
Smiles
O=C(O[Na])COC1=CC=CC(C[C@H]2C(C3=NC(C4=CC=CC=C4)=C(C5=CC=CC=C5)O3)=CCCC2)=C1
Molecular Formula
C30H26NNaO4
Molecular Weight
487.52
References & Citations
[1]Kouji Hattori , et al. A simple stereoselective synthesis and biological evaluation of FR181157: orally active prostacyclin mimetic. Bioorg Med Chem Lett. 2003 Dec 15;13 (24) :4277-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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