FR181157
Product Specifications
UNSPSC Description
FR181157, an orally active PGI2 agonist activity with especially good pharmacokinetic properties[1].
Target Antigen
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fr181157.html
Solubility
10 mM in DMSO
Smiles
O=C(O[Na])COC1=CC=CC(C[C@H]2C(C3=NC(C4=CC=CC=C4)=C(C5=CC=CC=C5)O3)=CCCC2)=C1
Molecular Weight
487.52
References & Citations
[1]Kouji Hattori , et al. A simple stereoselective synthesis and biological evaluation of FR181157: orally active prostacyclin mimetic. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4277-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120123/FR181157-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120123/
Clinical Information
No Development Reported
CAS Number
171046-15-4
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