Emicoron

Emicoron is a new promising G4 ligand and bind G-rich oncogene promoters. Emicoron possesses a marked antitumoral activity alone or in combination with chemotherapeutics in vivo. Emicoron can be used for cancer research[1].

Product Specifications

CAS Number

[1422423-23-1]

UNSPSC

12352005

Target

G-quadruplex

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/emicoron.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCN2CCCCC2)C3=C4C5=C(C6=C(C=C(C7=C6C8=C(C=C7C9=O)C(CCN%10CCCCC%10)=CC(C=C4C1=O)=C85)C(N9CCN%11CCCCC%11)=O)N%12CCCCC%12)C=C3

Molecular Formula

C52H58N6O4

Molecular Weight

831.05

References & Citations

[1]Manuela Porru, et al. EMICORON: A multi-targeting G4 ligand with a promising preclinical profile. Biochim Biophys Acta Gen Subj. 2017 May; 1861 (5 Pt B) :1362-1370.