Carazostatin

Carazostatin (DC118), an antioxidant, can be isolated from Streptomycs chromofuscus. Carazostatin (DC118) exhibits strong inhibitory activity against free radical-induced lipid peroxidation and shows stronger antioxidant activity in liposomal membranes than α-tocopherol (VE) [1].

Product Specifications

CAS Number

[126168-32-9]

Product Name Alternative

DC118

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/carazostatin.html

Solubility

10 mM in DMSO

Smiles

OC1=CC2=C(NC3=C2C=CC=C3)C(CCCCCCC)=C1C

Molecular Formula

C20H25NO

Molecular Weight

295.42

References & Citations

[1]Yuhzo Hieda, et al. Antioxidant effects of the highly-substituted carbazole alkaloids and their related carbazoles. Bioorg Med Chem Lett. 2014 Aug 1;24 (15) :3530-3.