GNX-865
GNX-865 is a mitochondrial permeability transition pore (mPTP) inhibitor that protects against ischemia-reperfusion injury in vivo[1].
Product Specifications
CAS Number
1223568-82-8
UNSPSC
12352005
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gnx-865.html
Purity
98.09
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C(/C=C/C1=CC=C(C(O)=C1)OC)NC2=CC=CC(Cl)=C2
Molecular Formula
C16H14ClNO3
Molecular Weight
303.74
References & Citations
[1]Fancelli D, et al. Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo. J Med Chem. 2014 Jun 26;57 (12) :5333-47.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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