BO-0742

BO-0742, a derivative of AHMA and N-mustard, is a potent anti-cancer agent. BO-0742 significantly suppresses the growth of xenografts of human breast and ovarian cancers in mice[1].

Product Specifications

CAS Number

[774234-08-1]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bo-0742.html

Solubility

10 mM in DMSO

Smiles

OCC1=CC(OCCN(CCCl)CCCl)=CC(NC2=C3C=CC=CC3=NC4=CC=CC=C42)=C1

Molecular Formula

C26H27Cl2N3O2

Molecular Weight

484.42

References & Citations

[1]Chien-Hsin Lee, et al. BO-0742, a derivative of AHMA and N-mustard, has selective toxicity to drug sensitive and drug resistant leukemia cells and solid tumors. Cancer Lett. 2009 Apr 18;276 (2) :204-11.