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Ataprost

Ataprost (ONO 41483) is an orally active Carboprostacyclin analogue. Ataprost exhibits 2.6 times more active than Carboprostacyclin in inhibiting ADP-induced platelet aggregation in vitro. Ataprost has the ability to relieve coronary spasm[1].

Product Specifications

CAS Number

83997-19-7

Product Name Alternative

ONO 41483

UNSPSC

12352211

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ataprost.html

Solubility

10 mM in DMSO

Smiles

O[C@@H](C1CCCC1)/C=C/[C@@H]2[C@](C/3)([H])[C@](CC3=C/CCCC(O)=O)([H])C[C@H]2O

Molecular Formula

C21H32O4

Molecular Weight

348.48

References & Citations

[1]Adaikan PG, et al. Inhibition of platelet aggregation and reversal of vasopressin-induced ECG changes by a carboprostacyclin analogue, ONO 41483, in primates. Prostaglandins Leukot Med. 1982 Sep;9 (3) :307-20.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

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