Tyrphostin AG1433 (hydrochloride)

Tyrphostin AG 1433 is a specific and potent inhibitor of PDGFR-β and of KDR/Flk-1. Tyrphostin AG 1433 acts as an angiogenesis inhibitor[1].

Product Specifications

CAS Number

[168836-03-1]

Product Name Alternative

SU1433 (hydrochloride) ; AG1433 (hydrochloride)

UNSPSC

12352005

Target

PDGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tyrphostin-ag1433-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C(C2=NC3=CC(C)=C(C)C=C3N=C2)C=C1O.[H]Cl

Molecular Formula

C16H15ClN2O2

Molecular Weight

302.76

References & Citations

[1]J Kroll, et al. The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J Biol Chem.1997 Dec 19;272 (51) :32521-7

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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