Tyrphostin AG1433 (hydrochloride)
Product Specifications
UNSPSC Description
Tyrphostin AG 1433 is a specific and potent inhibitor of PDGFR-β and of KDR/Flk-1. Tyrphostin AG 1433 acts as an angiogenesis inhibitor[1].
Target Antigen
PDGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tyrphostin-ag1433-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C2=NC3=CC(C)=C(C)C=C3N=C2)C=C1O.[H]Cl
Molecular Weight
302.76
References & Citations
[1]J Kroll, et al. The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J Biol Chem.1997 Dec 19;272(51):32521-7
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119757A/Tyrphostin-AG1433-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119757A/
Clinical Information
No Development Reported
CAS Number
168836-03-1
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