Tyrphostin AG1433 (hydrochloride)
Tyrphostin AG 1433 is a specific and potent inhibitor of PDGFR-β and of KDR/Flk-1. Tyrphostin AG 1433 acts as an angiogenesis inhibitor[1].
Product Specifications
CAS Number
[168836-03-1]
Product Name Alternative
SU1433 (hydrochloride) ; AG1433 (hydrochloride)
UNSPSC
12352005
Target
PDGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tyrphostin-ag1433-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C2=NC3=CC(C)=C(C)C=C3N=C2)C=C1O.[H]Cl
Molecular Formula
C16H15ClN2O2
Molecular Weight
302.76
References & Citations
[1]J Kroll, et al. The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J Biol Chem.1997 Dec 19;272 (51) :32521-7
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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