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Gossypolone

Product Specifications

UNSPSC Description

Gossypolone is an RNA-binding protein Musashi-1 inhibitor with a Ki of 12 nM. Gossypolone disrupts the Musashi-numb RNA interaction and directly binds to the RBD1 of MSI1 protein. Gossypolone can be used for the research of cancer[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gossypolone.html

Purity

96.63

Solubility

10 mM in DMSO

Smiles

O=CC1=C(C(O)=C(C2=C1C(C(C(C3=O)=C(C(C4=C3C(C=O)=C(C(O)=C4C(C)C)O)=O)C)=C(C2=O)C)=O)C(C)C)O

Molecular Weight

546.52

References & Citations

[1]Lan L, et al. Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins. BMC Cancer. 2018 Aug 10;18(1):809.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-119734/Gossypolone-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-119734/Gossypolone-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

4547-72-2

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