Antidesmone
Antidesmone is a isoquinoline alkaloid that can be isolated from Antidesma membranaceum[1]. Antidesmone can prevent acute lung injury in vivo via inhibiting MAPK and NF-κb activities[2].
Product Specifications
CAS Number
222629-77-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NF-κB; p38 MAPK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; NF-κB
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/antidesmone.html
Solubility
10 mM in DMSO
Smiles
O=C1C(OC)=C(C)NC2=C1[C@@H](CCCCCCCC)CCC2=O
Molecular Formula
C19H29NO3
Molecular Weight
319.44
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Buske, et al. Antidesmone, a novel type isoquinoline alkaloid from Antidesma membranaceum (Euphorbiaceae) . Tetrahedron, 55 (4), 1079–1086.|[2]Lu X, et al. Antidesmone, a unique tetrahydroquinoline alkaloid, prevents acute lung injury via regulating MAPK and NF-κB activities. Int Immunopharmacol. 2017 Apr;45:34-42.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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