Xanthopterin
Xanthopterin, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin (XPT) causes renal growth and hypertrophy in rat[1]. Xanthopterin inhibits RNA synthesis[4].
Product Specifications
CAS Number
119-44-8
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/xanthopterin.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=C(N=C1)NC(N)=NC2=O
Molecular Formula
C6H5N5O2
Molecular Weight
179.14
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Xanthopterin (XPT), an unconjugated pteridine compound, affects cell growth and differentiation. When injected into rats, XPT has caused changes that have been interpreted as renal growth and hypertrophy.|[2]Lord JL, et al. Cytotoxicity of xanthopterin and isoxanthopterin in MCF-7 cells. Cancer Lett. 2005 May 10;222 (1) :119-24.|[3]Plotkin M, et al. Xanthopterin in the Oriental hornet (Vespa orientalis) : light absorbance is increased with maturation of yellow pigment granules. Photochem Photobiol. 2009 Jul-Aug;85 (4) :955-61.|[4]Ziegler I, et al. Pterins and the regulation of lymphocyte activation on the mode of xanthopterin action. Hoppe Seylers Z Physiol Chem. 1984 Jun;365 (6) :667-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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