2- (3-Hydroxypicolinamido) acetic acid
2- (3-Hydroxypicolinamido) acetic acid is a 2OG oxygenase inhibitor with an IC50 value of 3.4 μM. 2- (3-Hydroxypicolinamido) acetic acid can be used as a functional probe for potential therapeutic research[1].
Product Specifications
CAS Number
3458-69-3
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-3-hydroxypicolinamido-acetic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(CNC(C1=NC=CC=C1O)=O)O
Molecular Formula
C8H8N2O4
Molecular Weight
196.16
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Woon EC, et al. Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase. J Med Chem. 2012 Mar 8;55 (5) :2173-84.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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