2- (3-Hydroxypicolinamido) acetic acid

2- (3-Hydroxypicolinamido) acetic acid is a 2OG oxygenase inhibitor with an IC50 value of 3.4 μM. 2- (3-Hydroxypicolinamido) acetic acid can be used as a functional probe for potential therapeutic research[1].

Product Specifications

CAS Number

[3458-69-3]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-3-hydroxypicolinamido-acetic-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(CNC(C1=NC=CC=C1O)=O)O

Molecular Formula

C8H8N2O4

Molecular Weight

196.16

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

References & Citations

[1]Woon EC, et al. Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic acid demethylase. J Med Chem. 2012 Mar 8;55 (5) :2173-84.