Clofibride
Clofibride is an orally active hypolipaemic agent of pchlorophenoxyisobutyric type. Clofibride has weak toxicity and marked hypocholesterolaemic and hypotriglyceridaemic activity. Clofibride is converted into 4-chlorophenoxyisobutyric acid (CPIB) and 4-hydroxy-N-dimethylbutyramide (HMB) in vivo[1].
Product Specifications
CAS Number
[26717-47-5]
UNSPSC
12352005
Target
Glutathione S-transferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/clofibride.html
Solubility
10 mM in DMSO
Smiles
CC(OC1=CC=C(C=C1)Cl)(C(OCCCC(N(C)C)=O)=O)C
Molecular Formula
C16H22ClNO4
Molecular Weight
327.80
References & Citations
[1]G P Loiseau, et al. On the metabolism of clofibride, a hypolipaemic drug. J Pharm Pharmacol. 1980 Jul;32 (7) :483-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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