Nizofenone
Nizofenone is a neuroprotective agent which protects neurons from death following cerebral ischemia or anoxia. Nizofenone can be used in the research of acute neurological conditions, such as stroke[1][2][3].
Product Specifications
CAS Number
54533-85-6
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nizofenone.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(Cl)C=CC=C1)C2=CC([N+]([O-])=O)=CC=C2N3C=CN=C3CN(CC)CC
Molecular Formula
C21H21ClN4O3
Molecular Weight
412.87
References & Citations
[1]Yi Liu, et al. Protective effects of nizofenone administration on the cognitive impairments induced by chronic restraint stress in mice. Pharmacol Biochem Behav. 2013 Jan;103 (3) :474-80. |[2]Y Matsumoto, et al. Nizofenone, a neuroprotective drug, suppresses glutamate release and lactate accumulation. Eur J Pharmacol. 1994 Sep 1;262 (1-2) :157-61. |[3]Y Miura, et al. [Effects of nizofenone on the action potential of guinea-pig papillary muscle and S-A node and dog Purkinje fibers]. |[4]H Yasuda, et al. Cerebral protective effect and radical scavenging action. J Neurochem. 1981 Oct;37 (4) :934-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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