Luotonin A

Luotonin A is an antiviral and antiphytopathogenic fungus agent. Luotonin A has good antiviral activity against tobacco mosaic virus (TMV) . Luotonin A also has certain inhibitory activity on topoisomerase I and topoisomerase II. Luotonin A shows antitumor activity[1][2].

Product Specifications

CAS Number

[205989-12-4]

UNSPSC

12352005

Hazard Statement

H301

Target

Fungal; TMV; Topoisomerase

Type

Natural Products

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/luotonin-a.html

Purity

98.03

Solubility

10 mM in DMSO

Smiles

O=C1N2C(C3=C(C2)C=C4C(C=CC=C4)=N3)=NC5=CC=CC=C51

Molecular Formula

C18H11N3O

Molecular Weight

285.30

Precautions

H301

References & Citations

[1]Hao Y, et al. Luotonin A and Its Derivatives as Novel Antiviral and Antiphytopathogenic Fungus Agents. J Agric Food Chem. 2020 Aug 19;68 (33) :8764-8773.|[2]Cagir A, et al. A naturally occurring human DNA topoisomerase I poison. J Am Chem Soc. 2003 Nov 12;125 (45) :13628-9.