Romifidine (hydrochloride)

Romifidine hydrochloride is an α2 adrenergic receptor agonist. Romifidine hydrochloride shows sedation effects in vivo[1][2].

Product Specifications

CAS Number

[65896-14-2]

UNSPSC

12352005

Hazard Statement

H301-H370

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/romifidine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

FC1=C(NC2=NCCN2)C(Br)=CC=C1.[H]Cl

Molecular Formula

C9H10BrClFN3

Molecular Weight

294.55

Precautions

P260-P264-P270-P330-P405-P501

References & Citations

[1]England GC, et al. A comparison of the sedative effects of three alpha 2-adrenoceptor agonists (romifidine, detomidine and xylazine) in the horse. J Vet Pharmacol Ther. 1992 Jun;15 (2) :194-201.|[2]Hamm D, et al. Sedative and analgesic effects of detomidine and romifidine in horses. Vet Rec. 1995 Apr 1;136 (13) :324-7.