MMP Inhibitor II
MMP Inhibitor II (compound 4e) is a potent, reversible pan-MMP inhibitor with IC50 values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1, MMP-3, MMP-7, and MMP-9, respectively[1].
Product Specifications
CAS Number
[203915-59-7]
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmp-inhibitor-ii.html
Purity
99.7
Solubility
DMSO : 20 mg/mL (ultrasonic; warming)
Smiles
O=C(C1N(S(=O)(C2=CC=C(C=C2)OC)=O)CC(C)(CN1S(=O)(C3=CC=C(C=C3)OC)=O)C)NO
Molecular Formula
C21H27N3O8S2
Molecular Weight
513.58
References & Citations
[1]S Pikul, et al. Discovery of potent, achiral matrix metalloproteinase inhibitors. J Med Chem. 1998 Sep 10;41 (19) :3568-71.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-1; MMP-3; MMP-7; MMP-9
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