AA-CW236

AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification[1].

Product Specifications

CAS Number

[1869921-96-9]

UNSPSC

12352005

Target

DNA Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aa-cw236.html

Purity

99.9

Solubility

DMSO : 25 mg/mL (ultrasonic; warming)

Smiles

FC(F)(F)OC1=CC=C(C2=C(CCl)N(CCC3=C(C)ON=C3C)N=N2)C=C1

Molecular Formula

C17H16ClF3N4O2

Molecular Weight

400.78

References & Citations

MGMT (O6-methylguanine DNA methyltransferase)

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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