AA-CW236
Product Specifications
UNSPSC Description
AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification[1].
Target Antigen
DNA Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aa-cw236.html
Purity
99.86
Solubility
DMSO : 25 mg/mL (ultrasonic;warming)
Smiles
FC(F)(F)OC1=CC=C(C2=C(CCl)N(CCC3=C(C)ON=C3C)N=N2)C=C1
Molecular Weight
400.78
References & Citations
[1]AA-CW236 is a <b>MGMT (O6-methylguanine DNA methyltransferase)</b> inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119390/AA-CW236-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119390/AA-CW236-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1869921-96-9
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