BNS

BNS is a cell penetrant, potent and selective PHD2 (prolyl-hydroxylase 2) inhibitor[1].

Product Specifications

CAS Number

[1417440-37-9]

UNSPSC

12352005

Target

HIF/HIF Prolyl-Hydroxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bns.html

Purity

96.17

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CC1=CS/C(N1O)=N\C(CS(=O)(CC2=CC=C3C=CC=CC3=C2)=O)=O)O

Molecular Formula

C18H16N2O6S2

Molecular Weight

420.46

References & Citations

[1]Leung IK, et al. Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors. J Med Chem. 2013 Jan 24;56 (2) :547-55.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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