BTI-A-404
BTI-A-404 is a potent, selective and competitive inverse agonist of human GPR43. BTI-A-404 can be used for the research of inflammation, obesity and type 2 diabetes[1].
Product Specifications
CAS Number
[537679-57-5]
UNSPSC
12352005
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bti-a-404.html
Purity
99.30
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC(C)=CC(C)=C1)C2=C(NC(NC2C3=CC=C(C=C3)N(C)C)=O)C
Molecular Formula
C22H26N4O2
Molecular Weight
378.47
References & Citations
[1]Park BO, et, al. Selective novel inverse agonists for human GPR43 augment GLP-1 secretion. Eur J Pharmacol. 2016 Jan 15;771:1-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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